Is THC-O Good for Inflammation?

by Kat Austin September 29, 2022 5 min read

Is THC-O Good for Inflammation? - Vida Optima™

Inflammation is at the source of most pain, chronic illnesses, and other health conditions that disrupt daily life. Unfortunately, taking non-steroidal anti-inflammatory drugs, otherwise known as NSAIDS, comes with a list of risky side effects, especially when used daily. So, it makes sense that many people are looking for other remedies, like THC and other cannabis-derived products.

THC-O, in particular, is known for being even more potent than traditional THC products. The question is–is THC-O good for inflammation? We don’t currently have much research about THC-O’s health benefits, but here’s how to decide for yourself:

Table of Contents
What is THC-O?
Research About THC-O for Inflammation
Can You Use THC-O for Inflammation?
Choosing the Best THC-O Product
THC-O Dosage
Is Using THC-O Safe?
Where to Buy THC-O Products

Key Takeaways

  • There’s not much research to help us understand THC-O’s medicinal potential, and most people use it recreationally.
  • Some people believe that THC-O may work for inflammation just based on its similarities to Delta-9-THC.
  • If you do choose to try THC-O for yourself, make sure you buy a high quality product.

What is THC-O?

THC-O is a legal hemp derivative with highly potent psychoactive effects. In fact, it's thought to be around three times more potent than traditional Delta-9-THC products. Aside from being stronger and federally legal, THC-O may provide many of the same therapeutic benefits as Delta-9-THC. This is because it interacts with the endocannabinoid system, a bodily system that plays a huge role in maintaining homeostasis, which includes regulating functions like body temperature, appetite, pain and inflammation signaling, and more. Much more research is needed to understand the practical and therapeutic applications of THC-O, but if it cancombat inflammation, it poses a much more accessible option for consumers across the country–especially those in states where medical marijuana is still prohibited.

Research About THC-O for Inflammation

Currently, there's almost no research to evaluate the specific therapeutic benefits that may be associated with THC-O. THC-O formulations are still incredibly new to the market, so research is expected to advance.

A bunch of indoor grown hemp material just before harvesting for research and cannabinoid production.

For now, experts predict that THC-O will have very similar effects to Delta-9-THC since it reacts similarly in the body. In fact, THC-O binds with the exact same receptor sites as Delta-9-THC, but at a higher rate, which explains it's increased potency. Some people predict that this may also translate to increased therapeutic effects. If this is the case, then THC-O will help to manage inflammation and pain similarly to, and maybe more effectively than traditional medicinal marijuana products.

Assuming that's true, we can turn to research on Delta-9-THC for inflammation to help us understand how THC-O may help. There have been multiple research efforts to confirm THC’s potential anti-inflammatory benefits, but the most prominent involved the use of THC for managing inflammatory bowel diseases like Crohn’s disease. In this study, THC was noted to have "clinical, steroid free benefits” for reducing inflammation. In general, medical marijuana is almost always approved for medical use for inflammatory conditions in areas where medicinal marijuana is legal.

Can You Use THC-O for Inflammation?

So, evidence is lacking to fully support any medicinal uses of THC-O, but does that mean you can't use THC-O for inflammation? You really have to decide for yourself.

Because it's so similar to Delta-9, it's undeniable that THC-O has therapeutic potential, but it's still unclear what that potential may be. And even if there were more evidence to help us understand how THC-O may help, there's still a caveat–everyone's endocannabinoid system is different, so everyone will respond a little differently to THC-O.

It boils down to this–you can absolutely try THC-O for managing inflammation, especially if you know that you respond well to using Delta-9-THC for inflammation, but do so at your own risk. Although many people enjoy THC-O's effects without negative effects, you still need to understand that it is incredibly potent. Because it's so strong, it's more likely to cause some adverse side effects with overuse. Plus, the hemp industry is still widely unregulated, so you have to do a little footwork to ensure that the THC-O you purchase is both safe and effective, which we will discuss in the section below.

If you choose to use THC-O for inflammation, especially if you want to use THC-O daily, you may want to consider experimenting with microdosing THC-O. Microdoses are small THC-O doses that generally will not produce psychoactive effects but may still provide the therapeutic effects of THC-O.

Choosing the Best THC-O Product for Inflammation

If you’ve decided to try THC-O for yourself, you definitely want to choose a high-quality THC-O product. Ideally, you should look for a product that is:

  • Made from high-quality, organic hemp material
  • Manufactured by experience technicians in a qualified facility
  • Free of pesticides, heavy metals, microbials, and other contaminants
  • Third-party lab tested to ensure label accuracy

Next, consider your actually dosing needs. For instance, some people looking to resolve inflammation may say they want a product that works quickly. Others may be more concerned with being able to meter the dosage, like you can do with a tincture. For those looking for the most potent doses possible, THC-O distillate may be the best option.

Vida Optima Elev8 THC-O Vape

Of course, THC-O vaporizers are increasingly popular because they mesh all of these qualities–fast acting, easy to dose, and potent. Our THC-O Vaporizers also contain Delta-8-THC and hemp-derived terpenes for strain profiling. This cannabinoid combination is designed to create a balanced effect that more closely replicated the effects of traditional Delta-9-THC than either cannabinoid can on its own.

We offer three different THC-O Vape formulas to choose from:

The Sativa THC-O Vape blend contains a total of 1,000 mg of Delta-8-THC and THC-O combined with a hand-chosen, sativa-leaning terpene blend designed to stimulate cognitive energy, boost creativity, and lift your spirits.

The Indica THC-O Vape blend also contain 1,000 mg of hemp-derived THC, but this terpene profile is designed to mellow you out, help you unwind, and provide a more body-centric relaxation experience.

The Hybrid THC-O Vape blend falls somewhere in the middle, offering a balanced, mellow buzz that’s still functional and uplifting

THC-O Dosage

Because THC-O is so potent, considering your dosage is paramount to ensuring a good THC-O experience. Too little THC-O and you may not feel any effects, but too much could increase the risk of experiencing side effects from THC-O.

Every person’s dosage varies, and the “average” dosage can range from 1-10 milligrams. We suggest starting with low doses and increasing slowly, especially if you are new to THC products. If you want to know more about THC-O Dosage, read “How Much THC-O Should I Take?

Is Using THC-O for Inflammation Safe?

Generally speaking, most people have a pleasant experience with THC-O, especially when using a high-quality product at responsible dosages. As with all THC products, side effects are still possible. The most common side effects associated with THC are red eyes, dry mouth, and increased heart rate.

The most important step you can take towards a safe THC-O experience is buying it from an experienced, high-quality hemp brand. The way that THC-O is made directly affects its quality and safety, so buying a well-made product is crucial. We also recommend that new users take dosing slowly until they understand how THC-O will affect them.

Read about THC-O safety and THC-O drug interactions to learn more.

Where to Buy THC-O for Inflammation

Thanks to updated hemp laws, THC-O is legal across the nation when made from hemp material. Of course, state laws vary, so you should also check to see if THC-O is legal in your local area before you buy.

Since it’s federally legal, you can easily buy THC-O online and have it shipped right to your door. Our THC-O Vapes contain Delta-8 and various therapeutic terpenes (hint: Indica strains may have better inflammation-relieving benefits). Check out our Elev8 Collection for a full selection of hemp-derived THC products you can buy online.


  1. “Cannabis Induces a Clinical Response in Patients With Crohn's Disease: A Prospective Placebo-Controlled Study”

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