April 19, 2022 3 min read

Tremella has long been used as a dietary supplement and anti-aging skincare treatment in many Eastern cultures, but modern research has recently unearthed even more reasons to add the medicinal mushroom to your daily wellness routine. Before you can get started with a daily Tremella dosage, you may have one important question–what are the side effects of Tremella mushrooms?

No stress! Here's what you need to know about Tremella side effects before adding it to your daily wellness routine:

Table of Contents
Is Tremella Safe?
What are the Side Effects of Tremella?
Tremella Drug Interactions
Is Tremella Additive?
Who Shouldn’t Take Tremella?
Tremella Side Effects FAQs

Key Takeaways

  • Tremella side effects are rare and almost always mild.
  • You may be at a higher risk for side effects if you have a mushroom allergy or take certain medications.
  • You should talk to your doctor before taking Tremella if you have blood sugar or thyroid problems.
  • Most people can take Tremella without any complications, but you need to choose a high quality supplement.

Is Tremella Safe?

Tremella is thought to be safe for most people who do not have an allergy to mushrooms. It’s an edible mushroom that’s used as part of a healthy diet in various parts of the world. It does, however, contain bioactive compounds called beta-glucans, as well as certain minerals and fibers that can react negatively with some people’s digestive system. Although side effects are incredibly rare and have not yet been well studied, there are some possible adverse reactions to be aware of before adding Tremella mushrooms to your skincare or wellness routine.

Raw tremella mushrooms before they are dried and encapsulated for daily supplement use.

What are the Side Effects of Tremella Mushrooms?

Based on anecdotal reports and what we know about medicinal mushrooms, Tremella side effects may include:


In rare cases, some consumers have reported feeling nauseous after using Tremella mushrooms, especially when taken raw or cooked.

Upset Stomach

Tremella mushrooms contain fiber that may be upsetting for some people’s digestive system. Symptoms like upset stomach, diarrhea, nausea, or gas could be a sign of an allergic reaction but it could also mean you’ve taken too much Tremella and should reduce your dosage.

Allergic Reaction

Although it is rare, some people experience a mushroom allergy. Symptoms of an allergic reaction to Tremella mushrooms may include:

  • Swelling of the lips, mouth, and airways
  • Difficulty breathing
  • Skin rashes or hives
  • Runny nose
  • Watery eyes
  • Nausea and vomiting
  • Stomach cramping
  • Bloating
  • Loose stools

Interactions With Other Supplements or Medications

In some cases, medicinal mushrooms like Tremella may interact with certain OTC and prescription medications, which could reduce their efficiency. We'll discuss this more below.

Tremella Drug Interactions

There is not much research regarding Tremella drug interactions, but it’s well documented that some functional mushrooms will interact with certain types of medications. You may be able to take Tremella alongside certain medications with a doctor's guidance and adjusted dosage. Talk to your doctor before taking Tremella if you take one of the following type of medications:

  • Antidepressants
  • Anti-anxiety medications
  • Thyroid medications
  • Blood pressure medications
  • Diabetes medications

Is Tremella Addictive?

Nope! Tremella does not possess any properties that may make it addictive. There is little to no potential for substance abuse for Tremella mushrooms.

Who Shouldn’t Take Tremella?

Most people can take Tremella without complication, and the mushroom is frequently eaten raw or prepared as part of traditional cuisines. Some experts advise against Tremella supplementation for the following people:

  • Those with bleeding disorders
  • Diabetics
  • Those with immune system disorders
  • Those expecting surgery in the next two weeks
  • Anyone with a thyroid disorder
  • Anyone taking blood pressure medication
  • Those who are pregnant or breastfeeding

Tremella Side Effects FAQ

Can you take Tremella everyday?

Yes, Tremella can be taken daily. You may need to take Tremella daily at or around the same time each day to experience its full benefits.

What does Tremella Do to your body?

Tremella mushrooms are said to have certain immune-boosting and anti-aging effects that may protect against cognitive degenerations and other signs of aging, but more research is needed to fully confirm any Tremella benefits.

Can Tremella mushrooms make me trip?

Nope! Tremella does not contain psilocybin or any other active chemicals that will produce psychoactive or hallucinogenic effects.

Do Tremella mushrooms cause side effects?

Tremella mushrooms are generally considered to be safe and there have not been any common or severe side effects reported. You should avoid medicinal mushrooms if you have a mushroom allergy and consult with your doctor before making any changes to your wellness routine, especially if you have one or more serious health conditions.

Can pregnant women take Tremella mushrooms?

There are no known side effects of Tremella, but the safety of functional mushrooms for pregnant women has not been tested. We recommend talking to your doctor before using Tremella if you are pregnant or breastfeeding.

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