L-Tyrosine Side Effects

by Kat Austin April 22, 2022 4 min read

L-Tyrosine Side Effects - Vida Optima™

L-Tyrosine is a non-essential amino acid, but supplementing with it daily has been linked to a wide range of benefits. Some sources suggest that L-Tyrosine can help balance the production of crucial neurotransmitters, like dopamine and adrenaline, which may help boost cognition, improve athletic performance, and regulate mood.

Before you can go all in on your L-Tyrosine dosing routine, though, you should make sure you understand which L-Tyrosine side effects to look out for and what to do when they arise. Before you get started, here's what you should know:

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Table of Contents
Is L-Tyrosine Safe?
What are the Side Effects of L-Tyrosine?
L-Tyrosine Drug Interactions
Is L-Tyrosine Addictive?
Who Shouldn’t Take L-Tyrosine?
L-Tyrosine Side Effect FAQs

Key Takeaways

  • L-Tyrosine side effects are rare and almost always mild.
  • L-Tyrosine should not be taken with some medications, like those designed to manage through disorders.
  • You should talk to your doctor before taking L-Tyrosine if you take other supplements or prescription medications daily.
  • Most people can take L-Tyrosine without any complications, but you need to choose a high quality supplement.
L-tyrosine powder, a dosing method commonly used for daily dosing or for pre-workout dosing.

Is L-Tyrosine Safe?

L-Tyrosine is non-essential, meaning it's naturally produced by the body and is essentially harmless in small to moderate doses. When a high-quality L-Tyrosine supplement is used, the risks of side effects is incredibly small. Of course, some mild side effects have been reported, and L-Tyrosine may not be the best choice for people with certain health conditions or who are taking certain medications. Here's what to look out for:

What are the Side Effects of L-Tyrosine?

Based on anecdotal reports and various trials, we know that L-Tyrosine side effects are rare and mild. Often, side effects are linked to poor product quality or adverse drug interactions. Some of the most commonly reported side effects include:

Allergic Reaction

L-Tyrosine is not known to pose any severe allergy threats for most people, but all supplements are made differently and some could cause allergic reactions. Get emergency medical help if you have signs of an allergic reaction, including:

  • Hives
  • Breathing difficulty
  • Swelling of the lips, tongue, face, or throat


Some people experience heartburn after taking L-Tyrosine, which could be caused by capsules becoming trapped in the upper digestive tract. Some people use antacids to remedy this, but you should also take capsules with plenty of water.


Medications that alter brain chemicals can possibly cause headaches, and headaches have been reported after taking larger L-Tyrosine doses. Generally, these headaches are rare and mild, but severe headaches should be reported to your healthcare provider who recommended L-Tyrosine supplementation.


Some people report feeling more tired than usual, especially in the first few weeks of dosing. Feeling slightly more tired is not a cause for concern but if you need extreme fatigue or lethargy, you should talk to your doctor before continuing your dosing routine.

Joint Pain

Some participants in clinical trials have reported experiencing increased joint pain after taking L-Tyrosine. Experts are not sure why this may be the case for some people, but if this happens to you, speak with your doctor about whether or not L-Tyrosine is right for you.

Interactions With Other Supplements or Medications

L-Tyrosine could interact with certain prescription and over the counter medications, so it's important to discuss supplementation with your doctor before you begin. We'll discuss this more below.

A bottle of prescription pills that may have adverse interactions with L-tyrosine

L-Tyrosine Drug Interactions

There is not much research regarding L-Tyrosine drug interactions, but sources suggest that it could interact with some medications, including prescription and over the counter drugs. You should seek medical advice before taking L-Tyrosine if you take any of the following medications:

  • Levodopa
  • Thyroid replacement therapies like Synthroid or Levothroid
  • Antidepressants
  • Anti-anxiety medications

Is L-Tyrosine Addictive?

No, L-Tyrosine is a naturally occurring amino acid and does not have the potential to be habit forming.

Who Shouldn't Take L-Tyrosine?

L-tyrosine is widely considered safe and can usually be taken without any adverse effects. There are a few situations where the use of L-tyrosine may not be recommended, especially without a doctor’s guidance.

You may want to avoid taking L-tyrosine if you:

  • Have an overactive thyroid
  • Have Graves disease
  • Are pregnant or breastfeeding
  • Take medications to alter hormones

You should always talk to your doctor when making changes to your wellness routine. Discontinue use of L-tyrosine if you experience any adverse reactions and talk with your doctor. Make sure that you source L-tyrosine from a trustworthy manufacturer since poor-quality formulations are the leading cause of adverse effects.

L-Tyrosine Side Effects FAQ

Can you take L-Tyrosine everyday?

Yes, research has found that taking L-Tyrosine daily for up to 6 months is safe for most people. There's no evidence to indicate that long term daily use is harmful, but you should talk to your doctor before taking L-Tyrosine for a period of longer than 6 months.

What happens if you take too much L-Tyrosine?

Taking too much L-Tyrosine could alter hormone balance, especially in people with the you'd issues or conditions like Grave's Disease. Read more about L-Tyrosine dosing to understand how to find your unique dosage threshold.

Does Tyrosine cause hair loss?

No. In fact, L-Tyrosine has been said to help reduce stress-induced hair loss and is one of the amino acids necessary for growing healthy hair.

Does Tyrosine work immediately?

L-tyrosine is metabolized quickly, meaning you may see benefits within 30 minutes of taking your supplements. Many people use L-Tyrosine in powdered form for even fast-acting effects, especially when it's used as a pre-workout supplement.

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