Can You Use Delta-10-THC for Nausea?

by Kat Austin April 25, 2023 6 min read

Can You Use Delta-10-THC for Nausea? - Vida Optima™

Delta-10 is known for inducing a smooth, mild euphoria that's roughly 25% as potent as traditional THC products. Its milder potency makes Delta-10's psychoactive effects much more approachable for new cannabis consumers.

The question is, is Delta-10 still therapeutically significant in the same ways as Delta-8 and Delta-9? More specifically, can the mild effects from Delta-10 still help to stave off nausea and vomiting?

The truth is, we don't have a lot of research to help us understand the therapeutic value of Delta-10-THC. We do know, however, that its interactions within the nervous system are almost identical to that of Delta-9 and Delta-8, so it's safe to assume that the benefits will be similar.

To better understand the possible benefits of Delta-10 for nausea, let's take a look at how other cannabinoids may calm nausea and how the mechanisms of D10 are similar.

Table of Contents
How It Works: Cannabinoids for Nausea
Can You Use Delta-10 for Nausea?
Will Delta-10 Increase Appetite?
Will Using Delta-10 for Nausea Get You High?
Does Delta-10 Have Any Side Effects?
How to Use Delta-10 for Nausea
What are the Best Delta-10 Products for Nausea?

Key Takeaways

  • Delta-10 has not been heavily researched, but may still have some therapeutic potential for relieving nausea.
  • Delta-10 may also help increase appetite, which is often useful when combating nausea.
  • Delta-10’s side effects are thought to be similar to traditional THC’s, meaning they are rare and mild.
  • There are many different types of Delta-10 products that may be useful for nausea, but you may want to avoid edible products.
A bottle of full spectrum CBD oil that may be used therapeutically to manage nausea

How It Works: Cannabinoids (& Delta-10) for Nausea

Many cannabinoids have been linked to potential antiemetic effects, or the ability to help manage nausea and vomiting. Delta-9-THC, the primary psychoactive component in traditional cannabis, is often used to help manage nausea and appetite problems related to chemotherapy, HIV/AIDS, cachexia, and other conditions.

According to research, delta-9 has potent antiemetic effects that are attributed to its ability to bind with both CB1 and CB2 receptors. THC notably has a high affinity for CB1 receptors, which is the neuroreceptor that's responsible for inducing psychoactive effects.

Other cannabinoids have a similar effect. For instance, CBD is thought to help reduce nausea through similar mechanisms. More specifically, CBD may mediate nausea by indirectly activating 5-HT1A receptors to regulate serotonin production. It is, after all, a build up of serotonin in the gut that causes nausea. This all happens via CB1 activation, similarly to THC.

Delta-8 is perhaps the closest relative to Delta-10-THC that we have actual data for. Delta-8 is also potentially the strongest of antiemetic cannabinoids. In fact, researchers believe that Delta-8's antiemetic properties are stronger than Delta-9's, potentially because its milder effects allow larger doses to be used.

In one pediatric study, Delta-8 was observed to be 100% effective at reducing nausea in children receiving chemotherapy. The researchers added that because Delta-8 was so mild, much larger doses could be given without adverse effects, possibly leading to greater efficacy.

Can You Use Delta-10-THC for Nausea?

So, what about Delta-10's effects on nausea? Even without research, we can assume that Delta-10 may have some benefits for helping to manage nausea. First, the reason that

Delta-10 is less potent than traditional THC products is because it has a lower affinity for CB1 receptors in the body. That means that it binds with the endocannabinoid system's psychoactive receptors at a lower rate than traditional THC. This is also the case with Delta-8, but this lower affinity doesn't seem to limit its anti-nausea potential.

In theory, this means that Delta-10-THC can provide even greater therapeutic benefits. The Delta-10 that doesn't bind with psychoactive receptors will bind elsewhere–possibly to CB2 receptors or other minor neuroreceptors responsible for various therapeutic effects. However, until there's more research available, it's hard to say what the therapeutic effects of Delta-10-THC may be. For now, we can only assume that they will be similar to the effects of Delta-8 and Delta-9, which we currently know more about.

Will Delta-10 Increase Appetite?

When you're experiencing nausea, it’s usually hard to eat, much less keep anything down. And that's unfortunate, because when you're sick you need as much nutrition and hydration as possible.

Luckily, Delta-10 may help stimulate appetite similarly to Delta-9-THC. In fact, anecdotal reports suggest that Delta-10 does induce a case of the munchies, though to a milder extent than other THC products. So, for a slight appetite boost that won't make you insatiable, Delta-10 may pull through.

Once again, there's no research available to help us understand how well Delta-10 may work for improving appetite. We do know a bit about its cannabinoid cousin, Delta-8-THC, though. A 2004 animal study found that Delta-8-THC stimulates appetite in mice. The research compared Delta-8-THC to Delta-9 and found Delta-8 to be more effective at stimulating appetite. Traditional THC, on its own, is so effective at increasing appetite that it's commonly recommended for patients with eating disorders or cachexia (wasting syndrome).

Will Using Delta-10 for Nausea Get You High?

Many people looking to experience Delta-10's therapeutic effects for nausea want to know if they'll also experience a THC high. The answer is maybe, but it really depends on your dosage and tolerance.

With stronger cannabinoids, like THC-O, many people use a microdosing technique to reap therapeutic benefits without experiencing heightened psychoactivity. Of course, since THC-O is nearly three times stronger than traditional THC products, you are likely to feel high even with small doses.

Delta-10, on the other hand, is already pretty mild, so small doses may only lead to a slight euphoria. In general, Delta-10’s effects are known to be mild but buzzy and uplifting, much unlike the sedating effects associated with other THC products.

Another option is to look at Delta-8-THC products. Delta-8 has been more heavily researched in regards to its benefits for nausea, and its psychoactive effects are still much milder than traditional THC products. They are, of course, more potent than Delta-10, but you can mediate psychoactive effects by lowering your dosage. You may be able to take Delta-8 at regular doses without getting too high, or you could microdose Delta-8 in order to reap its therapeutic benefits without any psychoactivity at all.

Does Delta-10 Have Any Side Effects?

Again, more research is needed to understand the safety profile of Delta-10. Assuming that the product is high-quality and free of potential contaminants, the most common side effects may be similar to that of other THC products. These potential side effects are usually rare and mild and may include:

  • Headaches
  • Increased heart rate
  • Dry mouth
  • Red eyes
  • Increased thirst
  • Hunger
  • Tiredness

Of course, the risks increase when using a low-quality product. The most severe risk in using a hemp-derived THC product is getting a product that is contaminated with residual solvents, pesticides, or other chemicals. That’s why it's important to only buy from high-quality, reputable brands that use clean hemp material and third-party testing techniques.

How to Use Delta-10 for Nausea

If you want to try Delta-10 for nausea, you’ll be happy to know that it's pretty straightforward. Here’s how to get started:

First, you may want to choose a fast-acting dosing method to combat nausea, because some products may take over an hour to kick in. A vaporizer can provide instant effects. It's also easy to stack on small doses every few minutes until you reach your desired effect, which is a great benefit to anyone who isn’t sure about their THC dosage.

Also note that the effects from a Delta-10 vape may last anywhere from 4 to 6 hours. That means you may need to take more than one dose throughout the day if your nausea persists.

Keep in mind that everyone's experience with hemp-derived THC is unique, so just pay close attention to how you feel and adjust your dosage amount and dosing routine accordingly. You may want to read “How Much Delta-10 Should I Take?” to learn more.

Elev8 25mg Delta 8 THC Gummies

What are the Best Delta-10 Products for Nausea?

Virtually any type of Delta-10 product will offer similar therapeutic benefits, as long as it’s a high-quality, uncontaminated product. Of course, many people prefer fast acting doses for combating nausea. Also, you'll probably want to avoid stocking up on Delta-10 edibles for this purpose, since it can be difficult to get any type of food down when you're feeling queasy.

Our recommendation for the best Delta-10 product for dealing with nausea? A Delta-10 or other hemp-derived THC vape. Our Hemp THC Vaporizers contain premium Delta-8-THC distillate and hand-selected terpenes to create a synergistic experience that’s balanced and therapeutically charged. THC vapes can be useful for new consumers, too, since the doses can be slowly stacked on one puff at a time.

Looking for premium hemp THC?Check out our Elev8 Collection. All Vida Optima products are made according to the industry’s highest standards and are 100% Farm Bill compliant.

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